Monday, February 6, 2012

Comparing Duodenal and Gastric Ulcers

In this post, you can see the dissimilarity of the two diseases in 4 categories such as 1. incidence, 2. signs and symptoms and clinical findings, 3. malignancy possibility, 4. risk factors.

To begin with the incidence, Duodenal ulcer occurs mostly at the age of 30-60 yrs old with a male:female ratio of 2-3:1 and some research shows that 80% of the peptic ulcers are duodenal while the Gastric ulcer usually occurs 50 yrs old and above with a male:female ratio of 1:1 and 15% of peptic ulcers are gastric.

In the category number 2 which is the signs, symptoms and the clinical findings, Duodenal ulcer occurs because of the hypersecretion of the stomach acid and may have a clinical manifestation of gaining weight. Moreover, pain occurs 2-3 hours after a meal, often awakened between 1-2AM and ingestion of food relives pain and thus gaining weight occurs. While the Gastric ulcer occurs due to normal to hyposecretion of stomach acid and weight loss may occur. In addition, pain occurs 1/2 to 1 hour after a meal, rarely occurs at night. It maybe relieve by vomiting and ingestion of food does not help and sometimes it increases pain.

Going to category 3 about the malignancy factors, Duodenal ulcer rarely become a factor to malignancy or cancer. On the other hand, Gastric ulcer occasionally part of malignancy factors that causes cancer.

Finally the category of risk factors, Duodenal ulcer can be triggered by the following risk factors like H.pylori, blood group O, chronic obstructive pulmonary disease (COPD), chronic renal failure, alcohol intake, smoking, liver cirrhosis and stress. However, Gastric ulcer has few risk factors compared to duodenal this are H.pylori, gastritis, alcohol intake, smoking, taking non steroidal anti-inflammatory drugs (NSAID's) and stress.

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